• Hormone references for ultrasound breast staging and endocrine profiling to detect female onset of puberty 

      Madsen, Andre; Bruserud, Ingvild Særvold; Bertelsen, Bjørn-Erik; Roelants, Mathieu; Oehme, Ninnie; Viste, Kristin; Bjerknes, Robert; Almås, Bjørg; Rosendahl, Karen; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Petur Benedikt (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-22)
      <p><i>Context - </i>Application of ultrasound (US) to evaluate attainment and morphology of glandular tissue provides a new rationale for evaluating onset and progression of female puberty, but currently no hormone references complement this method. Furthermore, previous studies have not explored the predictive value of endocrine profiling to determine female puberty onset. <p><i>Objective - </i>To ...
    • Low BMI, but not high BMI, influences the timing of puberty in boys 

      Oehme, Ninnie Helen Bakken; Roelants, Mathieu; Bruserud, Ingvild Særvold; Madsen, Andre; Bjerknes, Robert; Rosendahl, Karen; Juliusson, Pétur Benedikt (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-05)
      Background - Previous studies investigating the association between weight status and onset of puberty in boys have been equivocal. It is currently unclear to what extent weight class influences puberty onset and progression.<p> <p>Objectives - To explore the relationship between degree of sexual maturation and anthropometric measures in Norwegian boys.<p> <p>Methods - The following endpoints ...
    • Reference curves for pediatric endocrinology: leveraging biomarker z-scores for clinical classifications 

      Madsen, Andre; Almås, Bjørg; Bruserud, Ingvild Særvold; Oehme, Ninnie Helen Bakken; Nielsen, Christopher Sivert; Roelants, Mathieu; Hundhausen, Thomas Eckhard; Ljubicic, Marie Lindhardt; Bjerknes, Robert; Mellgren, Gunnar; Sagen, Jørn V.; Juliusson, Pétur Benedikt; Viste, Kristin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-03-17)
      Context: Hormone reference intervals in pediatric endocrinology are traditionally partitioned by age and lack the framework for benchmarking individual blood test results as normalized z-scores and plotting sequential measurements onto a chart. Reference curve modeling is applicable to endocrine variables and represents a standardized method to account for variation with gender and age.<p> <p>Objective: ...
    • References for ultrasound staging of breast maturation, tanner breast staging, pubic hair, and menarche in Norwegian girls 

      Bruserud, Ingvild Særvold; Roelants, Mathieu; Oehme, Ninnie; Madsen, Andre; Eide, Geir Egil; Bjerknes, Robert; Rosendahl, Karen; Juliusson, Petur Benedikt (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-06)
      <i>Context</i> - Discriminating adipose and glandular tissue is challenging when clinically assessing breast development. Ultrasound facilitates staging of pubertal breast maturation (US B), but has not been systematically compared to Tanner breast (Tanner B) staging, and no normative data have been reported.<p> <p><i>Objective</i> - To present normative references for US B along with references ...